What are the cardiovascular (CV) manifestations of P aeruginosa infection?

Updated: Dec 17, 2018
  • Author: Selina SP Chen, MD, MPH; Chief Editor: Russell W Steele, MD  more...
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Answer

Cardiovascular (CV) infections (eg, endocarditis, pericarditis, cardiac tamponade)

  • Pseudomonal infectious endocarditis (IE) affects normal and abnormal valves on both sides of the heart, resulting in valve destruction and heart failure. Biventricular and multiple valve infections are common in pseudomonal IE.

  • This organism has been isolated in patients with IE who abuse IV drugs, specifically pentazocine and tripelennamine (ie, "Ts" and "blues"). Individuals who abuse pentazocine and tripelennamine have a propensity for right-sided IE.

  • Fever is the most common symptom


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