What are the ophthalmologic manifestations of P aeruginosa infection?

Updated: Dec 17, 2018
  • Author: Selina SP Chen, MD, MPH; Chief Editor: Russell W Steele, MD  more...
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Answer

Eye infections (eg, endophthalmitis, keratitis, ophthalmia neonatorum, blepharoconjunctivitis, scleral abscess, orbital cellulitis)

  • Although pseudomonal eye infections are often associated with hydrophilic contact lens wear, infections have also been reported in patients who do not wear contact lenses.

  • Pseudomonal keratitis can present as a rapidly developing, necrotic, grayish stromal infiltrate in a bed of epithelial injury and surrounding edema. Disease progression varies but can rapidly progress and involve the entire cornea within 48 hours, leading to perforation. Fever and systemic symptoms are usually absent.

  • Pseudomonal corneal ulcers may lead to rapid loss of visual function and are considered a medical emergency.

  • Pseudomonal endophthalmitis progresses more rapidly than other bacterial infections. Clinical features may include pain, conjunctival hyperemia, chemosis, lid edema, decreased visual acuity, hypopyon, or severe anterior uveitis with involvement of the vitreous and panophthalmitis.


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