How does the prevalence of Pseudomonas infections vary among age groups?

Updated: Dec 17, 2018
  • Author: Selina SP Chen, MD, MPH; Chief Editor: Russell W Steele, MD  more...
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Answer

Infants younger than 1 year have direct vascular communication with the epiphysis across the growth plate, allowing direct spread of pseudomonal osteomyelitis from the metaphysis to the epiphysis and, eventually, the joint. In older children, the growth plate provides a barrier; thus, the epiphysis and the joints seldom are involved.

Children have a higher predilection than adults to pseudomonal osteochondritis infections following puncture wounds of the foot. Older patients are more susceptible to pseudomonal bone and joint infections. Children have a higher likelihood of developing pseudomonal folliculitis than adults. Endocarditis occurs most often in young (mean age 29 y) black men.

In patients with CF, prevalence of pseudomonal pneumonia ranges from 21% in those younger than 1 year to more than 80% in those older than 19 years. The increasing longevity of patients with CF has created a significant shift in the proportion of adult patients with CF; their proportion has increased 4-fold, from 8% in 1969 to 33% in 1990.


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