What are the genetic factors in pediatric urinary tract infection (UTI)?

Updated: Mar 19, 2019
  • Author: Donna J Fisher, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

Deregulation of candidate genes may predispose patients to recurrent UTIs. The identification of a genetic component may allow the identification of at-risk individuals and, therefore, prediction of the risk of recurrent UTI in their offspring. [5] Genes that are possibly responsible for susceptibility to recurrent UTIs include HSPA1B, CXCR1, CXCR2, TLR2, TLR4, and TGFβ1. [5]


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