How effective is maternal vaccination for infants for the prevention of pertussis (whooping cough)?

Updated: May 02, 2019
  • Author: Joseph J Bocka, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

A study by Kent et al found that maternal vaccination administered early in the third trimester may provide protection against pertussis and other pathogens for infants born prematurely. In the study, mothers of 31 (19%) of 160 premature infants received combined tetanus, diphtheria, 5-component acellular pertussis, inactivated polio vaccine in pregnancy. The study reported that compared with infants of unvaccinated mothers, those born to vaccinated mothers had significantly higher antibody concentrations at 2 months for all measured vaccine antigens. [41]

A CDC survey reported that 48.8% of pregnant women in the US received the Tdap vaccine in 2016, an increase from 42.1% in 2015. [42]

For the latest childhood and adolescent immunization recommendations, see the CDC immunization schedules. [35, 43]


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