What prophylaxis is available for people at risk for pertussis (whooping cough)?

Updated: May 02, 2019
  • Author: Joseph J Bocka, MD; Chief Editor: Russell W Steele, MD  more...
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The effectiveness of prophylaxis for exposed, susceptible persons has not been determined; however, it is recommended for household and close contacts of the patient. Regimens include the following:

  • Azithromycin (5 d)

  • Erythromycin (14 d)

  • Alternative regimen - Clarithromycin 7.5 mg/kg twice daily for 14 days (the effectiveness of clarithromycin has not been proven but is inferred)

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