What is the role of IgG titers in the diagnosis of measles?

Updated: Jun 06, 2019
  • Author: Selina SP Chen, MD, MPH; Chief Editor: Russell W Steele, MD  more...
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Answer

Measles-specific IgG titers

  • More than a 4-fold rise in IgG antibodies between acute and convalescent sera confirms measles

  • Acute specimens should be drawn on the seventh day after rash onset

  • Convalescent specimens should be drawn 10-14 days after that drawn for acute serum

  • The acute and convalescent sera should be tested simultaneously as paired sera


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