What is the role of IgM titers in the diagnosis of measles?

Updated: Jun 06, 2019
  • Author: Selina SP Chen, MD, MPH; Chief Editor: Russell W Steele, MD  more...
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Answer

Measles-specific IgM titers

  • Obtain blood on the third day of the rash or on any subsequent day up to 1 month after onset

  • The measles serum IgM titer remains positive 30-60 days after the illness in most individuals but may become undetectable in some subjects at 4 weeks after rash onset

  • False-positive results can occur in patients with rheumatologic diseases, parvovirus B19 infection, or infectious mononucleosis


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