How is measles exposure managed?

Updated: Jun 06, 2019
  • Author: Selina SP Chen, MD, MPH; Chief Editor: Russell W Steele, MD  more...
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Answer

Clinicians can best manage immunodeficient and immunosuppressed patients exposed to measles if they have previous knowledge of the patients' immune status.

Children should receive measles vaccination prior to treatment with biological response modifiers, such as tumor necrosis factor antagonists.

Susceptible patients with immunodeficiencies should receive immune globulin after measles exposure.

Warning against giving live-virus measles vaccines to immunocompromised patients with disorders associated with increased severity of viral infections (except people with HIV who do not have evidence of severe immunosuppression).

Recommendation not to give immunization for at least a month after a patient has finished a high-dose course of corticosteroids, such as prednisone.


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