What is the role of lab tests in the diagnosis of Legionella infection?

Updated: Nov 13, 2018
  • Author: Mobeen H Rathore, MD, CPE, FAAP, FIDSA; Chief Editor: Russell W Steele, MD  more...
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Answer

General laboratory testing in patients with Legionnaires disease (LD) reveals several nonspecific abnormalities. [11]

Hematologic studies may reveal leukocytosis or leukopenia with left shift, thrombocytosis, or thrombocytopenia with disseminated intravascular coagulopathy (DIC).

Erythrocyte sedimentation rate and C-reactive protein levels are elevated.

Chemistry studies may reveal elevated aminotransferase levels, hyponatremia (more commonly associated with Legionnaires disease than with other pneumonias in adults), hypophosphatemia, elevated creatine kinase levels, and other abnormalities. These abnormalities are not as common in children as they are in adults.

Urinalysis commonly reveals proteinuria and hematuria.


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