Should children with pediatric HIV infection receive a rotavirus vaccination?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

The potential risks and benefits of administering rotavirus vaccine to infected infants must be considered because immunocompromised hosts sometimes have severe, prolonged, and even fatal rotavirus gastroenteritis. However, safety or efficacy data are not available for the administration of rotavirus vaccine to infants with HIV/AIDS and other clinical manifestations of HIV infection. Data from clinical trials are insufficient to support the administration of rotavirus vaccine to infants with indeterminate HIV status who were born to mothers with HIV/AIDS.


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