Why is medication compliance difficult in pediatric HIV infection?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

The treatment regimen may be difficult. Patients must take multiple doses of several ARDs every day, as well as prophylactic antibiotics and supplemental vitamins. Therefore, the risk of missing a dose is high. New ARDs are being developed to simplify the medical regimen. The simplest dosing regimen should be carefully selected to help avoid this pitfall.

Noncompliance with prescribed medications is multifactorial and major in some populations. In general, children do not like to take medications, especially if they taste bad. Several drugs have an unpleasant taste. Adverse effects (eg, GI upset, diarrhea, allergy) may cause the caretaker to discontinue a medication without informing the physician. Many drugs can cause compliance problems, even in the most reliable individuals.


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