How is toxoplasmosis acquired in pediatric HIV infection and which tests are indicated when it is suspected?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

Toxoplasmosis is a rare CNS infection in children. When it occurs, it is usually acquired congenitally.

Specific immunoglobulin G and immunoglobulin M titers, as well as head ultrasonography to detect CNS lesions, should be performed in neonates with risk of congenital infection or in whom it is suspected. Treatment with pyrimethamine, folinic acid, and sulfadiazine or clindamycin is required when infection occurs.


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