What are the signs and symptoms of disseminated M avium-intracellulare complex (MAC) infection in pediatric HIV infection?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

Although localized pulmonary disease is the common form of infection in hosts not infected with HIV, localized disease is uncommon in HIV-infected individuals, and disseminated disease is typical. Disseminated MAC infections commonly cause fever, night sweats, malaise, anorexia, and weight loss. Anemia and elevated alkaline phosphatase levels are also common. Involvement of the bone marrow may produce neutropenia.


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