What is the role of prophylaxis of viral infections in pediatric HIV infection?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

Previous CMV infection or CMV retinitis requires secondary prophylaxis with ganciclovir 5 mg/kg/day IV, or valganciclovir, or an implant delivering sustained-release ganciclovir or cidofovir.

Severe or frequent recurrences of herpes simplex require prophylaxis with acyclovir 80 mg/kg/d given by mouth 2 or 4 times day.

Varicella or herpes zoster should be treated with IV acyclovir 500 mg/m2/dose 3 times a day for 7 days.


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