How is treatment initiated in neonates at risk of vertically acquired pediatric HIV infection?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
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Within 6-12 hours of the delivery of a neonate at risk, zidovudine therapy should be started after a baseline CBC count is obtained. Zidovudine should be continued until the infant is 6 weeks of age, when it may be discontinued if all DNA HIV PCR results are negative. If HIV infection is confirmed in the infant, zidovudine monotherapy must be stopped immediately.

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