How can drug interactions among antiretroviral agents be beneficial in the treatment of pediatric HIV infection?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

Drug interactions among antiretroviral agents may be used to increase and sustain serum levels of one another, enhancing efficacy and decreasing adverse effects (eg, Kaletra, which is a fixed-dose combination product of lopinavir and ritonavir). Other interactions may decrease levels, causing concern about sufficient efficacy. Discussion of drug interactions can be found in Antiretroviral Therapy for HIV Infection.


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