How are adverse effects of drug interactions minimized in pediatric HIV infection?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

Antiretroviral drug (ARD) regimens often contain 3 or more agents. In addition, other drugs are typically required to manage the numerous infectious and systemic consequences of AIDS.

Therefore, the likelihood of drug interactions increases. The outcome of the drug interactions may reduce or eliminate the efficacy or increase the toxicity of 1 or both drugs. A thorough understanding of the mechanisms of interactions is essential to minimize or prevent adverse effects and to prevent inadequate treatment.


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