How effective is lopinavir/ritonavir combination therapy in children younger than 6 years with HIV-1 infection?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

One study evaluated the use of lopinavir/ritonavir combination therapy in children younger than 6 years with HIV type 1 infection who have not undergone highly active antiretroviral therapy (HAART). Seventy percent of the 43 children in the study realized a virologic success at month 12. Overall, 20 children experienced virologic failure; risk factors for virologic failure were determined to be young age and low socioeconomic status. [43]


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