Which antiretroviral therapy (ART) regimens are effective in achieving viral suppression in pediatric HIV infection?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

A study by Cotton et al found that fosamprenavir/ritonavir–containing regimens in HIV-infected children aged 4 weeks to 2 years achieved plasma amprenavir exposures comparable to those of regimens approved in adults (except for trough exposures in infants under age 6 months). Viral suppression was achieved in 61% of patients, and the regimens were generally well tolerated, with the most common adverse events being diarrhea, upper respiratory tract infection, gastroenteritis, and otitis media. [42]


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