How do reverse transcriptase inhibitors (NRTIs, NNRTIs) work in pediatric HIV infection?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

The reverse transcriptase inhibitors (NRTIs, NNRTIs) suppress HIV replication by competitive inhibition of viral reverse transcriptase. PIs prevent the late stages of viral replication by interfering with the formation of structural proteins of the virion core.


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