What is the role of CD4+ lymphocyte count in monitoring disease progression in pediatric HIV infection?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

The CD4+ lymphocyte count is a surrogate marker for disease progression and should be monitored closely. The CD4+ count should be obtained before therapy. A rapid decrease in the count, especially in infants younger than 1 year, is a poor prognostic sign and should prompt the start or alteration of therapy.


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