What are the expected patterns of viral loads in vertically acquired HIV infection in infants?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
  • Print
Answer

Initial infection is associated with high viral loads, especially in the neonate. In adults and adolescents with nonvertically acquired infections, the viral load rapidly decreases 6-12 months after the primary viremia. Neonates have high viral loads that persist throughout infancy; therefore, these values are hard to interpret in the first year of life. In children with vertically acquired infections, the load slowly declines after 1 year of age. The predictive value of specific HIV RNA concentrations for disease progression and death for an individual child in the first year of life is moderate.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!