How is the viral load quantified in the workup of pediatric HIV infection?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

The viral load can be quantified by using several HIV assays. The number of virions in the peripheral blood is an important indicator of disease activity and of the effectiveness of antiretroviral therapy (ART). A 5- or 3-fold change in the viral load is needed to reliably indicate a clinically significant change in children younger than 2 years or older than 2 years, respectively.


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