What is the manifestation of measles infections in children where pediatric HIV infection is endemic?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

In regions of the world where measles vaccination is not routinely administered and where HIV is endemic, the potential for serious measles infection exists. [7, 24] Measles typically manifests with an erythematous macular eruption of the trunk with caudal spread. Koplik spots (small blue-white dots surrounded by erythematous rings on the buccal mucosa) are the most common oral manifestation. In children who are immunocompromised, measles may manifest without skin involvement but with more severe complications.

Death from pneumonitis and encephalitis has been reported in African children with both HIV infection and measles.


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