What is the role of Pneumocystis jiroveci (formerly P carinii) pneumonia (PCP) in AIDS and how does it manifest in pediatric HIV infection and AIDS?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

Pneumocystis jiroveci (formerly P carinii) pneumonia (PCP) is the primary AIDS-defining illness and occurs in 7-20% of patients who have not been administered prophylaxis and are younger than 1 year. Most commonly, PCP manifests as cough, dyspnea, tachypnea, and fever. The incidence of PCP is declining in areas where AIDS medications are available, but it continues to shorten life expectancy in areas in which access to antiretrovirals is limited.


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