What is the prognosis of HIV-infected children in resource-poor nations?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
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In resource-poor nations, the progression to death is accelerated. In some instances, close to 45-90% of HIV-infected children died by the age of 3 years. However, among children and adolescents, the start of combination therapy including protease inhibitors reduces the intermediate-term risk of death by an estimated 67%. Also, host genetics play an important role in HIV-1–related disease progression and neurologic impairment

The patient's overall progression and prognosis is followed up by using the CDC classification system for children infected with HIV (see Staging).

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