What do CD95+ T-cell levels indicate in HIV infection?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

The CD95/Fas receptor/ligand system is necessary for the apoptosis of T cells, and abnormalities in this system are linked with increased T-cell death in patients who are HIV positive. As the immune status deteriorates, an increase in CD95+ T cells is found; conversely, a low CD95+ T-cell count is found in asymptomatic patients who are HIV positive.


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