What causes the immunocompromised state and the proliferation of opportunistic infections and malignancies in pediatric HIV infection?

Updated: Mar 05, 2020
  • Author: Delia M Rivera, MD; Chief Editor: Russell W Steele, MD  more...
  • Print
Answer

The reduction in cell-mediated immunity and secondary B-cell dysfunction result in the immunocompromised state and in the proliferation of opportunistic infections and malignancies. An elevated level of activation-induced cell death resulting from apoptosis of T cells occurs in patients who are HIV positive.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!