What are the possible complications of pediatric factor VII deficiency?

Updated: Jun 22, 2021
  • Author: Helge Dirk Hartung, MD; Chief Editor: Hassan M Yaish, MD  more...
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Complications may include the following:

  • Recurrent bleeding, particularly hemarthroses, which can result in progressive damage to joints and chronic arthropathy. Management of recurrent hemarthroses applies the principles used in hemophilia care.

  • A risk of thrombosis can be associated with the combination of surgery and factor VII replacement therapy using prothrombin complex concentrate or high doses of factor VII concentrates.

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