Which conditions are included in the differential diagnoses of pediatric factor XIII (FXIII) deficiency?

Updated: Mar 15, 2019
  • Author: Helge Dirk Hartung, MD; Chief Editor: Cameron K Tebbi, MD  more...
  • Print
Answer

Acquired factor XIII (FXIII) deficiency can be caused by liver disease, inflammatory bowel disease, and disseminated intravascular coagulation, although controversy surrounds whether the low plasma levels in these conditions actually contribute to clinical bleeding. The development of autoantibodies to factor XIII has been reported. Consider other congenital coagulation factor deficiencies, most notably afibrinogenemia.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!