What is the role of pulmonary function tests in the workup of Langerhans cell histiocytosis (LCH)?

Updated: Sep 16, 2020
  • Author: Cameron K Tebbi, MD; Chief Editor: Vikramjit S Kanwar, MBBS, MBA, MRCP(UK), FAAP  more...
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Answer

When pulmonary involvement occurs, pulmonary function may be abnormal. [127, 128] Diffuse cystic changes, nodular infiltrate, pleural effusion, and pneumothorax are known to occur. Pulmonary function tests may reveal restrictive lung disease with decreased pulmonary volume and are critical components of follow-up in patients with pulmonary involvement. [127, 128]


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