Which lymphatic disorders are included in the differential diagnoses of Langerhans cell histiocytosis (LCH)?

Updated: Sep 16, 2020
  • Author: Cameron K Tebbi, MD; Chief Editor: Vikramjit S Kanwar, MBBS, MBA, MRCP(UK), FAAP  more...
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Answer

Lymphatic disorders

In patients with localized disease (especially those in whom solitary nodes are present), malignant lymphoma, malignant histiocytosis, metastatic disorders, and leukemic infiltrates, and (uncommonly) Spitz nevus and mastocytosis must be considered. The differential diagnosis of enlarged lymph nodes also includes infectious disorders, granulomatous diseases, and lymphomas.


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