What are the signs and symptoms of pediatric chronic granulomatous disease (CGD)?

Updated: Aug 07, 2019
  • Author: Lawrence C Wolfe, MD; Chief Editor: Cameron K Tebbi, MD  more...
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Answer

The hallmark of CGD is early onset of severe, recurrent bacterial and fungal infections. Common presentations of the condition include the following:

  • Skin infections

  • Pneumonia

  • Lung abscesses

  • Suppurative lymphadenitis

  • Diarrhea secondary to enteritis

  • Perianal or perirectal abscesses

  • Hepatic or splenic abscesses

Another characteristic manifestation of CGD is the development of granulomas in the skin, gastrointestinal (GI) tract, and genitourinary (GU) tract.


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