What are the causes of basophilia in leukocytosis, and what is the relation of leukocytosis to coronavirus disease 2019 (COVID-19)?

Updated: May 19, 2020
  • Author: Susumu Inoue, MD; Chief Editor: Jennifer Reikes Willert, MD  more...
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Answer

A basophil count that exceeds 0.10-0.15 X 109/L (100-150/μL) that leads to leukocytosis is rare. Chronic myelogenous leukemia (adult type) typically exhibits basophilia and leukocytosis as described above (see Malignancy and myeloproliferative disorder).

COVID-19

A literature review by Huang et al suggested that in contrast with patients who have mild cases of COVID-19, those with severe cases tend to have leukocytosis and lymphopenia. [33]


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