What is the role of LMWH in the treatment of antithrombin III (ATIII) deficiency?

Updated: Feb 10, 2018
  • Author: James L Harper, MD; Chief Editor: Hassan M Yaish, MD  more...
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Answer

LMWH has been used to treat patients with heterozygotic gene mutations; however, as LMWH depends on antithrombin III for activity, anti-Xa activity levels should be closely monitored and doses should be adjusted to maintain anti-Xa activity levels in the 0.5-1 international units/mL.


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