When is a central venous line indicated in children with antithrombin III (ATIII) deficiency?

Updated: Mar 04, 2020
  • Author: James L Harper, MD; Chief Editor: Hassan M Yaish, MD  more...
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Given the significant risk of venous thrombosis associated with central venous line (CVL) placement in children without signs of antithrombin III deficiency, those children known to have a congenital antithrombin III deficiency should have CVLs placed only if significant need outweighs increased potential risk of a clinically significant clot.

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