What is the focus of clinical history for the diagnosis of antithrombin III (ATIII) deficiency?

Updated: Feb 10, 2018
  • Author: James L Harper, MD; Chief Editor: Hassan M Yaish, MD  more...
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Answer

Antithrombin III (ATIII) deficiency is most commonly associated with venous thrombosis. Guidelines for VTE have been established. [13] History should focus on current symptoms, defining the patient's personal medical history in terms of thrombosis and thrombotic symptoms, as well as determining if other procoagulant risk factors are present. Often, children with antithrombin III deficiency present with unusual clot locations (eg, mesenteric veins, splenic veins).


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