Which medications in the drug class Nonsteroidal Anti-inflammatory Drugs are used in the treatment of Lumbosacral Facet Syndrome?

Updated: Nov 19, 2018
  • Author: Gerard A Malanga, MD; Chief Editor: Craig C Young, MD  more...
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Nonsteroidal Anti-inflammatory Drugs

NSAIDs offer anti-inflammatory benefits compared with acetaminophen. The dose needed to achieve an anti-inflammatory benefit is significantly greater than that needed for an analgesic effect. Risks are associated with NSAIDs, especially in elderly persons or persons with peptic ulcer disease, hypertension, or renal insufficiency. Newer-generation NSAIDs selectively interact with the cyclooxygenase (COX)-2 receptors and have a lower GI risk. Prolonged use of these medications is generally not recommended for most low back dysfunctions.

Ibuprofen (Ibuprin, Motrin, Advil)

DOC for mild to moderate pain. Inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis.

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