How are the complications of Prader-Willi syndrome (PWS) prevented?

Updated: Oct 14, 2020
  • Author: Ann Scheimann, MD, MBA; Chief Editor: Luis O Rohena, MD, MS, FAAP, FACMG  more...
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  • Patients with Prader-Willi syndrome have hyperphagia and require restricted access to foods to minimize weight gain. Binge-eating episodes may predispose patients to development of food poisoning and acute gastric dilation. Caregivers of patients with Prader-Willi syndrome should be instructed in the Heimlich maneuver. [35]

  • Evaluate males with Prader-Willi syndrome and cryptorchidism for gonadotropin-releasing hormone (GnRH) and orchiopexy. [42]

  • Routinely monitor for symptoms of sleep apnea. Obtain a sleep study within the few months after initiation of growth hormone therapy at the first sign of symptoms. [10]

  • Routinely screen children for scoliosis. [52, 8]

  • Regularly screen patients with obesity for evidence of type 2 diabetes mellitus. [42]

  • Screen for thyroid and adrenal function when indicated. [8]

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