What are the possible endocrine complications of Down syndrome?

Updated: Apr 30, 2018
  • Author: Gratias Tom Mundakel, MBBS, DCH; Chief Editor: Maria Descartes, MD  more...
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Answer

Thyroid dysfunction, particularly acquired hypothyroidism, is relatively common in Down syndrome. Because of the increased risk, thyroid function tests should be performed in the newborn, repeated at ages 6 and 12 months, and then performed annually. Hyperthyroidism can also develop. In addition, type I diabetes mellitus occurs with higher frequency in Down syndrome.


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