Which cutaneous findings are characteristic of Down syndrome?

Updated: May 18, 2020
  • Author: Gratias Tom Mundakel, MBBS, DCH; Chief Editor: Maria Descartes, MD  more...
  • Print

Skin disorders occur in up to 80% of children with Down syndrome. Xerosis, localized hyperkeratotic lesions, elastosis serpiginosa, alopecia areata (< 10%), vitiligo, folliculitis (especially common in adolescents), abscess formation, and recurrent skin infections are observed. [29, 30] Distal axial triradius in the palms, transverse palmar creases, a single flexion crease in the fifth finger, ulnar loops (often 10), a pattern in hypothenar, and interdigital III regions are observed. [31]

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!