What is the role of medications in the treatment of arthrogryposis multiplex congenita (AMC)?

Updated: Nov 11, 2020
  • Author: Mithilesh Kumar Lal, MD, MBBS, MRCP, FRCPCH, MRCPCH(UK); Chief Editor: Maria Descartes, MD  more...
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Answer

Drug therapy is not currently a component in the standard of care for this condition. Evidence indicates, however, that genetic mutations associated with endplate components play a role in arthrogryposis and pterygium formation. Acetylcholine treatment, together with physical therapy, seems to elicit a response from some of these pterygium syndromes, the apparent result of causing an increase in endplate function. [42]


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