What are the indications for an autopsy following a death due to arthrogryposis multiplex congenita (AMC)?

Updated: Jan 03, 2019
  • Author: Mithilesh K Lal, MD, MBBS, MRCP, FRCPCH, MRCPCH(UK); Chief Editor: Maria Descartes, MD  more...
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Answer

An autopsy should be performed to discover more about the following:

  • CNS (ie, brain neuropathology)

  • Spinal cord (number and size of anterior horn cells, presence or absence of tracts at various levels)

  • Ganglia and peripheral nerves

  • Eye (ie, neuropathology)

  • Muscle tissue from different muscle groups (ie, electron microscopy and special stains)

  • Fibrous bands replacing muscle

  • Tendon attachments

  • Other visceral anomalies, malformations, deformations, and disruptions


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