How are malignancies treated in pediatric breast disorders?

Updated: Apr 01, 2019
  • Author: Harsh Grewal, MD, FACS, FAAP; Chief Editor: Robert K Minkes, MD, PhD  more...
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Answer

Answer

The most common malignant mass in the breast of a child or adolescent is a metastatic lesion.

Ashikdri et al reviewed the world literature between 1888 and 1977 and found a total of 74 cases of carcinoma of the breast in children and adolescents. [26] Initial surgical options for infiltrating lobular or intraductal carcinoma in adolescents include breast-sparing surgery (ie, lumpectomy with axillary node dissection and irradiation) and modified radical mastectomy. Younger women tend to have more aggressive disease.

Systemic adjuvant chemotherapy is strongly advised in all young women with breast carcinoma. No concrete recommendations regarding the use of endocrine methods (ie, ovarian ablation) in the treatment of breast cancer in these women are available. [27] Other primary malignancies of the breast include rhabdomyosarcoma and Hodgkin disease. [28] Metastatic disease in children is more often rhabdomyosarcoma. [29]


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