What is the role of medications in the treatment of intussusception?

Updated: Dec 20, 2018
  • Author: A Alfred Chahine, MD; Chief Editor: Carmen Cuffari, MD  more...
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Drug therapy is not currently a component of the standard of care for intussusception. Medications are limited to those used for pain control after surgery. In the immediate postoperative period, weight-adjusted intravenous morphine is usually administered. As the oral diet is resumed, acetaminophen with codeine or ibuprofen is given orally.

Patients with HSP or hemophilia and intussusception require standard therapy for the individual disease. Some investigators have advocated the use of steroids in intussusception secondary to HSP and lymphoid hyperplasia, with varied results.

A Cochrane review reported that as an adjuvant therapy to reduce recurrence rates, Dexamethasone may be more effective following air or liquid enema. However, these results were based on a few small studies and further research is necessary. [30]

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