What is the role of Henoch-Schönlein purpura (HSP) in the etiology of intussusception?

Updated: Dec 20, 2018
  • Author: A Alfred Chahine, MD; Chief Editor: Carmen Cuffari, MD  more...
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Children with HSP often present with abdominal pain secondary to vasculitis in the mesenteric, pancreatic, and intestinal circulation. If pain precedes cutaneous manifestations, differentiating HSP from appendicitis, gastroenteritis, intussusception, or other causes of abdominal pain is difficult.

Occasionally, children with HSP develop submucosal hematomas, which can act as lead points and cause small bowel intussusception. Elucidating the cause of the pain is essential in any child in whom HSP is suspected.

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