What is the relationship between pediatric gastroesophageal reflux disease (GERD) and respiratory tract disease?

Updated: Mar 14, 2019
  • Author: Steven M Schwarz, MD, FAAP, FACN, AGAF; Chief Editor: Carmen Cuffari, MD  more...
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Some patients have atypical symptoms (eg, nocturnal cough, wheezing, or hoarseness as the only major complaint). Gastroesophageal reflux is a complicating factor in asthma. The mechanism may include microaspiration, which leads to reflex bronchoconstriction. The association of gastroesophageal reflux and airway or respiratory tract disease is common. Cough, stridor, and pharyngitis have all been linked to gastroesophageal reflux. In addition, an association with rumination is commonly observed in patients with developmental delay.

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