Which medications in the drug class Antibiotics, macrolides are used in the treatment of Pediatric Helicobacter Pylori Infection?

Updated: Nov 16, 2018
  • Author: Mutaz I Sultan, MBChB, MD; Chief Editor: Carmen Cuffari, MD  more...
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Answer

Antibiotics, macrolides

The macrolide used in the treatment of H pylori infection is stable in the gastric environment, enters the bacterial cell, binds to receptors on the ribosomal subunits, and inhibits bacterial protein synthesis.

Clarithromycin (Biaxin)

Provides bacteriocidal activity against H pylori with antimicrobial spectrum similar to that of erythromycin but more stable in acid environment and has fewer adverse GI effects. Available as granules for susp 125 or 250 mg/5 mL and film tab: 250 or 500 mg.


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