Which medications in the drug class Bismuths are used in the treatment of Pediatric Helicobacter Pylori Infection?

Updated: Nov 16, 2018
  • Author: Mutaz I Sultan, MBChB, MD; Chief Editor: Carmen Cuffari, MD  more...
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Answer

Bismuths

Bismuth subsalicylate and bismuth subcitrate have complementary effects with most antimicrobials. Bismuth disrupts bacterial cell walls. Bismuth is particularly effective in lysing the cell wall of the organism when the organism is close to the gastric epithelium and relatively inaccessible to most antimicrobial agents.

Bismuth subsalicylate (Pepto-Bismol)

Lyses bacterial cell walls, prevents organism adhesion to epithelium, and inhibits urease.

Available as (subsalicylate) chewable tab 262 mg and liquid 262 mg or 525 mg/15 mL.


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